产品展示
DENND2CMAP激酶激活死亡域蛋白2C抗体
点击次数：229发布时间：2012/12/5 13:19:57
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-9667R
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详细内容
货号：BY-9667R
英文名称：Anti-DENND2C
中文名称：MAP激酶激活死亡域蛋白2C抗体
其他名称：名DENN/MADD domain containing 2C;dJ1156J9.1;DKFZp686G0351;DKFZp686N1631;DKFZp779P1149;FLJ37099;RP5-1156J9.1.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 107kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, dog, cow, dog
产品介绍：DENND2C is a 928 amino acid protein that contains a dDENN domain, a DENN domain, ａnd a uDENN domain ａnd exists as three isoforms as a result of alternative splicing. The DENND2C protein is thought to target to actin filaments ａnd control Rab9-dependent trafficking of mannose-6-phosphate receptor to lysosomes. The gene encoding DENND2C maps to human chromosome 1, the largest human chromosome which spans about 260 million base pairs ａnd makes up 8% of the human genome. Other notable genes located on chromosome 1 include LMNA, which is associated with the rare aging disease Hutchinson-Gilford progeria, ａnd the MUTYH gene, which is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease ａnd Usher syndrome.
