本公司经销DCN/Decorin，核心蛋白聚糖抗体，克隆类型为polyclonal，宿主来源是Rabbit，DCN/Decorin核心蛋白聚糖抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-1695R
英文名称：Anti-DCN/Decorin
中文名称：核心蛋白聚糖抗体
其他名称：名Decorin; Bone proteoglycan II; CSCD; DCN; DCN protein; Dermatan sulphate proteoglycans II; DKFZp686J19238; DSPG 2; DSPG2; PG 40; PG II; PG S2; PG40; PGII; PGS 2; PGS2; Proteoglycan core protein; SLRR1B; Small leucine rich protein 1B.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 40kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, pig, cow, shp, hrs, Gpig, Rb, chk
产品介绍：Decorin is a member of the small, leucine rich proteoglycan （SLRP） family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen ａnd other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor （EGFR）, ａnd TGF beta. It is believed that decorin also plays a role in the cell cycle of chondrocytes. Also known as: Decorin; Bone proteoglycan II; CSCD; DCN; DCN protein; Dermatan sulphate proteoglycans II; DKFZp686J19238; DSPG 2; DSPG2; PG 40; PG II; PG S2; PG40; PGII; PGS 2; PGS2; Proteoglycan core protein; SLRR1B; Small leucine rich protein 1B.Function : May affect the rate of fibrils formation.Subcellular Location : Secreted > extracellular space > extracellular matrix.Post-translational modifications : The attached glycosaminoglycan chain can be either chondroitin sulfate or dermatan sulfate depending upon the tissue of origin.DISEASE : Defects in DCN are the cause of congenital stromal corneal dystrophy （CSCD） [MIM:610048]. Corneal dystrophies are inherited, bilateral, primary alterations of the cornea that are not associated with prior inflammation or secondary to systemic disease. Most show autosomal dominant inheritance.Similarity : Belongs to the small leucine-rich proteoglycan （SLRP） family. SLRP class I subfamily.Contains 12 LRR （leucine-rich） repeats.核心蛋白聚糖（decorin）属高分子蛋白多糖类，为蛋白聚糖（PG）的一种,是转化生长因子β（TGFβ）的拮抗剂。Decorin在调节细胞粘附、迁移、增殖、胶原纤维形成活性调节及对TGF-β的负反馈调节中起到一定的作用。