产品展示
DRP3/Dystrobrevin alpha肌营养蛋白α抗体
点击次数：177发布时间：2012/12/5 13:38:19
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-10046R
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详细内容
货号：BY-10046R
英文名称：Anti-DRP3/Dystrobrevin alpha
中文名称：肌营养蛋白α抗体
其他名称：名Dystrobrevin alpha; DRP3; DTN; DTNA; Dystrophin related protein 3; FLJ96209; LVNC1; OTTHUMP00000163154; OTTHUMP00000163155; D18S892E.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 63kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo,rat, pig, dog, hrs, cow
产品介绍：Dystrobrevin alpha belongs to the dystrobrevin subfamily of the dystrophin family. It is a component of the dystrophin associated protein complex （DPC）, which consists of dystrophin ａnd several integral ａnd peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins ａnd alpha ａnd beta dystrobrevin. The DPC localizes to the sarcolemma ａnd its disruption is associated with various forms of muscular dystrophy. Dystrobrevin alpha may be involved in the formation ａnd stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors. Mutations in Dystrobrevin alpha are associated with left ventricular noncompaction with congenital heart defects.Subunit : Homotetramer, ａnd heterotetramer with CRMP1, DPYSL2, DPYSL4 or DPYSL5 （By similarity）.Subcellular Location : Cytoplasm. Cell projection, growth cone.Tissue Specificity : Mainly expressed in heart ａnd skeletal muscle. Also strongly expressed in fetal brain ａnd spinal cord.Similarity : Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
