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货号：BY-4307R
英文名称：Anti-beta 2 Defensin
中文名称：防御素β2抗体
其他名称：名BD 2;BD-2;BD2;beta 2;Beta defensin 2;Beta-defensin 2;Beta-defensin 4A;DEF B2;DEF B4;DEFB 102;DEFB 2;DEFB 4;DEFB102;DEFB2;DEFB4;DEFB4B;Defensin;Defensin beta 2;Defensin beta 4;DFB4A_HUMAN;HBD 2;hBD-2;HBD2;SAP 1;SAP1 antibodySkin antimicrobial peptide 1;Skin-antimicrobial peptide 1.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 7kDa
纯化方法：affinity purified by Protein A
交叉反应：hu
产品介绍：Beta-defensins （also designated BD, ａnd hBD in human） are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia ａnd neutrophils of several species, Beta-defensins are developmentally regulated. Human b-defensin 2 is locally regulated by inflammation ａnd is the first member of the b-defensin family that is locally inducible by inflammation. The murine homolog of human b-defensin 2, which is called b-defensin 3, is present in the respiratory system ａnd in low levels in the epithelial cells of the intestine ａnd lung. The unique murine b-defensin 2 （Defb2） is not expressed in airways of untreated mice, but is upregulated in the airways by lipopolysaccharide ａnd may contribute to host defense at the mucosal surface of the airwaysFunction : Has antibacterial activity.Subcellular Location : Secreted.Tissue Specificity : Expressed in the skin ａnd respiratory tract.Similarity : Belongs to the beta-defensin family. LAP/TAP subfamily.
