产品展示
DAB2IPDab2相互作用蛋白抗体
点击次数：244发布时间：2012/12/5 13:43:23
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-5998R
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详细内容
货号：BY-5998R
英文名称：Anti-DAB2IP
中文名称：Dab2相互作用蛋白抗体
其他名称：名AF9Q34; AIP1; ASK interacting protein; ASK interacting protein 1; ASK1 interacting protein 1; DAB2 interacting protein; DAB2 interaction protein; DAB2P; DIP1/2; Disabled homolog 2 interacting protein; DOC 2/DAB2 interactive protein; nGAP like protein.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 118kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, dog, pig, Gpig, cow, hrs
产品介绍：DAB2IP is a Ras GTPase-activating protein （GAP） that acts as a tumor suppressor gene ａnd is inactivated by methylation in prostate ａnd breast cancers. It also interacts with MAP3K5 to disrupt the association of MAP3K5 with the inhibitory 14-3-3 complex.Subcellular Location : Membrane. Cytoplasm. Note: Translocates to the cytoplasm in response to TNF.Tissue Specificity : Low expression in prostate. Down-regulated in prostate cancer.Similarity : Contains 1 C2 domain.Contains 1 PH domain.Contains 1 Ras-GAP domain.
