产品展示
DNAJC7DNAJC7蛋白抗体
点击次数：267发布时间：2012/12/5 13:56:07
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-8280R
优质供应
详细内容
货号：BY-8280R
英文名称：Anti-DNAJC7
中文名称：DNAJC7蛋白抗体
其他名称：名DnaJ homolog subfamily C member 7; Tetratricopeptide repeat protein 2; TPR repeat protein 2; TPR2; TTC2.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 56kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cow, pig, hrs, dog, chk, Rb
产品介绍：The DnaJ family is one of the largest of all the chaperone families ａnd has evolved with diverse cellular localization ａnd functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli ａnd are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide-binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis ａnd are in-volved in the regulation of protein degradation, exocytsis ａnd endocytosis. DnaJC7 （DnaJ homolog subfamily C member 7）, also known as TPR2, TTC2 or DANJC7, is ubiquitously expressed, with highest expression in testis, liver, heart ａnd brain.Subunit : Associates with complexes containing chaperones HSP70 ａnd HSP90. Interacts with the GAP domain of NF1. Interacts with HSP90AA1. Interacts with HSPA1A/B; the interaction is enhanced by ATP. Interacts with HSP90AB1. Interacts with PGR. Interacts with RAD9A; the interaction is interrupted by UV ａnd heat shock treatments. Interacts with HUS1 ａnd RAD1. Interacts with NR1I3. The DNAJC7-NR1I3 complex may also include HSP90 （By similarity）. Interacts with HSPA8.Subcellular Location : Cytoplasm. Nucleus. Cytoplasm, cytoskeleton.Similarity : Contains 1 J domain.Contains 9 TPR repeats.
