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货号:BY-6641R
英文名称:Anti-DNA Ligase 1
中文名称:DNA连接酶1抗体
其他名称:名DNA ligase 1; DNA ligase I; Polydeoxyribonucleotide synthase [ATP] 1.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, Rb, pig, cow, dog, hrs
产品介绍:Eukaryotic DNA ligases are ATP-dependent enzymes that catalyse the joining of single and double-strand DNA breaks, which is an essential final step in DNA replication, recombination and repair. Four biochemically distinct DNA ligases, termed ligases I-IV, have been identified in mammalian cells. DNA ligase I is functionally homologous to the DNA ligase encoded by the Saccharomyces cerevisiae Cdc9 gene. The joining of Okazaki fragments during lagging strand DNA replication in mammalian cells is due to DNA ligase I."