产品展示
DMT1/Dematin金属离子转运体1抗体
点击次数:376发布时间:2012/12/5 14:25:32
更新日期:2024/9/5 14:43:01
所 在 地:中国大陆
产品型号:BY-3577R
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详细内容
货号:BY-3577R
英文名称:Anti-DMT1/Dematin
中文名称:金属离子转运体1抗体
其他名称:名DCT 1; DCT1; Divalent metal transporter 1; DMT 1; Natural resistance associated macrophage protein 2; NRAMP 2; NRAMP2.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 62kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, rat, mo, cow
产品介绍:DMT1 is a major transporter of ferrous iron from the intestinal lumen. DMT1 belongs to the family of NRAMP metal ion transporters which function in diverse organisms from bacteria to human. DMT1 (NRAMP2) transports metal ions at the plasma membrane of cells of both the duodenum and in peripheral tissues, and defective DMT1 causes anaemia.Function : Actin-bundling protein. May function in mitogen-activated protein kinase pathway.Subcellular Location : Cytoplasm.Tissue Specificity : Heart, brain, lung, skeletal muscle, and kidney.Post-translational modifications : Actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase.Similarity : Belongs to the villin/gelsolin family.Contains 1 HP (headpiece) domain.