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DAAM1形态发生紊乱关联激活因子1抗体
点击次数:173发布时间:2012/12/5 14:26:08
更新日期:2024/9/5 14:43:01
所 在 地:中国大陆
产品型号:BY-4099R
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货号:BY-4099R
英文名称:Anti-DAAM1
中文名称:形态发生紊乱关联激活因子1抗体
其他名称:名DAAM 1; DAAM-1; Dishevelled associated activator of morphogenesis 1; FLJ41657; KIAA0666.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 120-130kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat
产品介绍:DAAM1 (Dishevelled associated activator of morphogenesis 1) is a diaphanous-related formin which binds to dishevelled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex assembly. It is an essential component of noncanonical Wnt signaling. DAAM1 also communicates with Rho GTPases, CIP4 and Src in the regulation of the signalling pathways that co-ordinate the dynamics of the actin filament system. DAAM1 may be a coordinator of endocytosis and cytoskeletal remodeling.DAAM1是蓬乱蛋白相关形态形成活化因子1或称形态发生紊乱关联激活因子1,为形成素蛋白家族的成员。Daam1是WNT/PCP通路的组成因子,参与细胞的内吞功能,可调节细胞骨架的形成与构建.