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DPP2溶酶体丝氨酸蛋白酶DPP2抗体
点击次数：257发布时间：2012/12/5 14:28:28
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-6045R
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详细内容
货号：BY-6045R
英文名称：Anti-DPP2
中文名称：溶酶体丝氨酸蛋白酶DPP2抗体
其他名称：名Dipeptidyl aminopeptidase II; Dipeptidyl peptidase 7; Dipeptidyl peptidase II; DPP II; DPP2; DPP7; DPPII; QPP; Quiescent cell proline dipeptidase.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 52kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：DPP2 is a serine protease found most abundantly in the lysosome. There is also a non-lysosomal membrane-associated form of DPP2 reported in the rat brain （DPP-II-M）, ａnd a soluble form （DPP-II-S）. First discovered as an enzyme involved in the terminal steps of protein degradation, ａnd later as an enzyme involved in cell growth ａnd quiescence, DPP2 cleaves N-terminal dipeptides ａnd tripeptides from proteins. DPP2 has a preference for proline in the P1 position, ａnd processes the tripeptides generated by DPP1 （which is unable to cleave if proline is in the P1 position）. Some tumor cell lines express elevated DPP2 levels, ａnd serum levels of DPP2 are elevated in some cancer patients, making DPP2 a potential tumor marker. DPP2 levels have been also been reported to be elevated in the cerebral spinal fluid from Parkinson’s patients.Function : Plays an important role in the degradation of some oligopeptides.Subunit : Homodimer.Subcellular Location : Lysosome. Cytoplasmic vesicle. Secreted.Tissue Specificity : Detected in seminal plasma （at protein level）.Post-translational modifications : N-glycosylated.Similarity : Belongs to the peptidase S28 family.
