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DIS3L2有丝分裂控制蛋白样DIS3L2抗体
点击次数：202发布时间：2012/12/5 14:31:52
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-9053R
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详细内容
货号：BY-9053R
英文名称：Anti-DIS3L2
中文名称：有丝分裂控制蛋白样DIS3L2抗体
其他名称：名DIS3 L2;DIS3 mitotic control homolog （S. cerevisiae） like 2;DIS3 mitotic control homolog like 2;FLJ36974;MGC42174.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 63kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cow, dog, pig
产品介绍：The exosome is a multisubunit complex composed of several highly conserved subunits, some of which are 3’ to 5’ exoribonucleases. The complex is involved in a variety of cellular processes ａnd is responsible for degrading unstable mRNAs that contain AU-rich （ARE） elements in their untranslated 3’ region. DIS3L2 （DIS3-like exonuclease 2） is an 885 amino acid protein that is thought to function as an exonuclease ａnd may be required for the 3’ processing of pre-mRNA into mature mRNA. Defects or chromosomal translocations involving the gene encoding DIS3L2 may be associated with Marfanoid habitus, a genetic disorder characterized by abnormalities in the skeleton, eyes ａnd cardiovascular system. DIS3L2 is expressed as five isoforms due to alternative splicing events.
