本公司经销phospho-ER-beta（ser105），磷酸化雌激素受体β抗体，克隆类型为polyclonal，宿主来源是Rabbit，phospho-ER-beta（ser105）磷酸化雌激素受体β抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-6451R
英文名称：Anti-phospho-ER-beta（ser105）
中文名称：磷酸化雌激素受体β抗体
其他名称：名Estrogen Receptor beta （phospho S105）; p-ER beta; ER BETA;ER-beta;Erb;ESR 2;ESR B;ESR BETA;ESR2;ESR2_HUMAN;ESRB;ESTRB;Estrogen Receptor 2;Estrogen receptor beta;NR3A2;Nuclear receptor subfamily 3 group A member 2.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 66kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo
产品介绍：Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, ａnd activates expression of reporter genes containing estrogen response elements （ERE） in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability ａnd has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 ａnd ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol ａnd 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.Subcellular Location : Nucleus.Tissue Specificity : Tissue specificityIsoform beta-1 is expressed in testis ａnd ovary, ａnd at a lower level in heart, brain, placenta, liver, skeletal muscle, spleen, thymus, prostate, colon, bone marrow, mammary gland ａnd uterus. Also found in uterine bone, breast, ａnd ovarian tumor cell lines, but not in colon ａnd liver tumors. Isoform beta-2 is expressed in spleen, thymus, testis ａnd ovary ａnd at a lower level in skeletal muscle, prostate, colon, small intestine, leukocytes, bone marrow, mammary gland ａnd uterus. Isoform beta-3 is found in testis. Isoform beta-4 is expressed in testis, ａnd at a lower level in spleen, thymus, ovary, mammary gland ａnd uterus. Isoform beta-5 is expressed in testis, placenta, skeletal muscle, spleen ａnd leukocytes, ａnd at a lower level in heart, lung, liver, kidney, pancreas, thymus, prostate, colon, small intestine, bone marrow, mammary gland ａnd uterus. Not expressed in brain.