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FBXO36FBXO36 F-box蛋白相关蛋白36抗体
点击次数:201发布时间:2012/12/5 14:37:17
更新日期:2024/9/5 14:43:01
所 在 地:中国大陆
产品型号:BY-8470R
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详细内容
货号:BY-8470R
英文名称:Anti-FBXO36
中文名称:FBXO36 F-box蛋白相关蛋白36抗体
其他名称:名F box only protein 36;F box protein 36;F-box only protein 36;Fbx 36;Fbx36;FBX36_HUMAN;FBXO 36;Fbxo36;FLJ37592;FLJ41090.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat
产品介绍:FBXO36 is a 188 amino acid protein that contains one forty amino acid F-box region, making it a member of the F-box family. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-å and ∫-catenin, for degradation by the proteasome after ubiquitination. Functioning as a component of the SCF complex, FBXO36 is thought to recognize and bind to select phosphorylated proteins, thereby promoting their ubiquitination and subsequent degradation."