产品展示
ENAH/MENAENAH蛋白抗体
点击次数:321发布时间:2012/12/5 14:38:21
更新日期:2024/9/5 14:43:01
所 在 地:中国大陆
产品型号:BY-9660R
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详细内容
货号:BY-9660R
英文名称:Anti-ENAH/MENA
中文名称:ENAH蛋白抗体
其他名称:名ENA;Enah;ENAH_HUMAN;MENA;NDPP1;Protein enabled homolog.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 67kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat
产品介绍:Function : Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin rich outgrowths in fibroblasts. Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation. Required for the actin-based mobility of Listeria monocytogenes.Subcellular Location : Cytoplasm.Tissue Specificity : Expressed in myoepithelia of parotid, breast, bronchial glands and sweat glands. Expressed in colon-rectum muscolaris mucosae epithelium, pancreas acinar ductal epithelium, endometrium epithelium, prostate fibromuscolar stroma and placenta vascular media. Overexpressed in a majority of breast cancer cell lines and primary breast tumor lesions.Similarity : Belongs to the Ena/VASP family.Contains 1 WH1 domain.