产品展示
Phospho-Estrogen Receptor alpha (Ser167)磷酸化雌激素受体ER alpha 抗体
点击次数:201发布时间:2012/12/5 14:43:51
更新日期:2024/9/5 14:43:01
所 在 地:中国大陆
产品型号:BY-0894R
优质供应
详细内容
货号:BY-0894R
英文名称:Anti-Phospho-Estrogen Receptor alpha (Ser167)
中文名称:磷酸化雌激素受体ER alpha 抗体
其他名称:名estrogen receptor; DKFZp686N23123; ER alpha; ER; Era; ESR 1; ESR; ESR1; ESRA; Estradiol receptor; Estrogen receptor 1; Estrogen receptor; Major ORF; NR3A1
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 66kDa
纯化方法:affinity purified by Protein A
交叉反应:hu
产品介绍:Estrogen and progesterone receptor are members of a family of transcription factors that are regulated by the binding of their cognate ligands. The interaction of hormone-bound estrogen receptors with estrogen responsive elements(EREs) alters transcription of ERE-containing genes. The carboxy terminal region of the estrgen receptor contains the ligand binding domain, the amino terminus serves as the transactivation domain, and the DNA binding domain is centrally located. Two forms of estrogen receptor have been identified, ER Alpha and ER Beta. ER Alpha and ER Beta have been shown to be differentially activated by various ligands. The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (hPR-A and hPR-B), which arise from alternative splicing. In most cells, hPR-B functions as a transcriptional activator of progesterone-responsive gene, whereas hPR-A function as a transcriptional inhibitor of all steroid hormone receptors.产品图片Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-Phospho-Estrogen Receptor alpha (Ser167) Polyclonal Antibody, Unconjugated (bs-0894R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) stainingTissue/cell: human placenta tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-Phospho-Estrogen Receptor alpha (Ser167) Polyclonal Antibody, Unconjugated (bs-0894R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining