产品展示
EAAT1/Glast胶质细胞谷氨酸运载蛋白1抗体
点击次数：277发布时间：2012/12/5 14:46:29
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-1003R
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详细内容
货号：BY-1003R
英文名称：Anti-EAAT1/Glast
中文名称：胶质细胞谷氨酸运载蛋白1抗体
其他名称：名EA6; EAAT1; Excitatory amino acid transporter 1; FLJ25094; GLAST; GLAST1; Glial high affinity glutamate transporter; High affinity neuronal glutamate transporter; Slc1a3; Sodium dependent glutamate/aspartate transporter.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 56kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, rat, mo
产品介绍：Transports L-glutamate ａnd also L- ａnd D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. [SUBCELLULAR LOCATION] Membrane; Multi-pass membrane protein. [TISSUE SPECIFICITY] Highly expressed in cerebellum, but also found in frontal cortex, hippocampus ａnd basal ganglia. [SIMILARITY] Belongs to the sodium: dicarboxylate （SDF） symporter（TC 2.A.23） family.Function : Transports L-glutamate ａnd also L- ａnd D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.Subunit : Belongs to the sodium:dicarboxylate （SDF） symporter （TC 2.A.23） family. SLC1A3 subfamily.Subcellular Location : Membrane.Tissue Specificity : Highly expressed in cerebellum, but also found in frontal cortex, hippocampus ａnd basal ganglia.DISEASE : Defects in SLC1A3 are the cause of episodic ataxia type 6 （EA6） [MIM:612656]. EA6 is characterized by episodic ataxia, seizures, migraine ａnd alternating hemiplegia.EAAT-1主要用于神经胶质细胞的损伤及退变方面的研究.
