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EBNA 3AEB病毒核抗原-3A抗体
点击次数：198发布时间：2012/12/5 14:47:43
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-0820R
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货号：BY-0820R
英文名称：Anti-EBNA 3A
中文名称：EB病毒核抗原-3A抗体
其他名称：名EBNA 3A; EBV; Epstein Barr virus; HHV4; Nuclear antigen EBNA 3A; EBNA 3A; Epstein-Barr nuclear antigen 3; EBV nuclear antigen 3; EBNA-3; Epstein-Barr nuclear antigen 3A; EBV nuclear antigen 3A.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 103kDa
纯化方法：affinity purified by Protein A
交叉反应：EBV/HHV4
产品介绍：EBNA3A is a latent viral nuclear protein expressed in Epstein Barr Virus （EBV） transformed lymphoblastic cell lines. It is also found in some immunoblastic lymphomas in vivo. This viral nuclear protein is essential for EBV mediated transformation of B lymphocytes. The EBNA3A functions as a transcriptional regulator though the target genes are currently unknown.Function : Plays an essential role for activation ａnd immortalization of human B-cells. Represses transcription of viral promoters TP1 ａnd Cp through interaction with host RBPJ, ａnd inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop.Subunit : Interacts with human UCKL1. Interacts with host CTPB1; this interaction seems important for EBNA3-mediated transcriptional repression. Interacts with host RBPJ.Subcellular Location : Host nucleus matrix. Note=Associated with the nuclear matrix.Similarity : Belongs to the herpesviridae EBNA-3 family.EB病毒核抗原-3（nuclear antigen EBNA-3）是EB病毒编码核蛋白，位于细胞核的新的酶聚合体，主要作为转录调节因子，指导蛋白与蛋白之间相互作用，为核糖核苷酸补救途径的一部分.
