产品展示
ESPL1外纺锤体极样蛋白1抗体
点击次数：189发布时间：2012/12/5 14:51:49
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-4101R
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详细内容
货号：BY-4101R
英文名称：Anti-ESPL1
中文名称：外纺锤体极样蛋白1抗体
其他名称：名Caspase like protein ESPL1; ESP 1; ESP1; ESP-1; ESPL 1; ESPL1; ESPL-1; Extra spindle poles like 1; Extra spindle poles like 1 protein; Separin; Similar to fission yeast cut1and gene; SSE.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 198kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：Separase is a cysteine protease that is essential for mitotic progression by separating sister chromatids. Each cell must receive one chromatid of every chromosome, during mitosis. Cohesin plays an important role in cohering sister chromatids during the prophase through anaphase stages of mitosis, making certain that genomic information is replicated accurately. As the cellular division process continues, separase destroys cohesin by means of cleavage, allowing the chromatids to separate ａnd divide with the cell. Separase activity is highly regulated. It not only cleaves cohesin at the onset of anaphase but also cleaves itself, promoting downregulation of separase after anaphase. Should a human cell become an aneuploid （one too many or too few chromatids）, the embryo most likely will not survive. Should the embryo survive, it will most likely develop severe birth defects or later develop malignant cancers.Subcellular Location : Cytoplasmic ａnd Nuclear
