产品展示
EPHA10酪氨酸蛋白激酶受体A10抗体
点击次数:477发布时间:2012/12/5 15:27:35
更新日期:2024/9/5 14:43:01
所 在 地:中国大陆
产品型号:BY-6636R
优质供应
详细内容
货号:BY-6636R
英文名称:Anti-EPHA10
中文名称:酪氨酸蛋白激酶受体A10抗体
其他名称:名EPH receptor A10; EPHA 10; Epha10; EphA10s protein; EPHAA_HUMAN; Ephrin type A receptor 10; Ephrin type-A receptor 10.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 110kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, dog, hrs, cow, Rb, chk, pig
产品介绍:The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date (1–3). While the biological activities of these receptors have yet to be determined, there is increasing evidence that they are involved in central nervous system function and in development (1–3). The Eph subfamily receptors of human origin (and their murine/avian homologs) include EphA1 (Eph), EphA2 (Eck), EphA3 (Hek4), EphA4 (Hek8), EphA5 (Hek7), EphA6 (Hek12), EphA7 (Hek11/MDK1), EphA8 (Hek3), EphB1 (Hek6), EphB2 (Hek5), EphB3 (Cek10, Hek2), EphB4 (Htk), EphB5 (Hek9) and EphB6 (Mep). Ligands for Eph receptors include ephrin-A4 (LERK-4) which binds EphA3 and EphB1. In addition, ephrin-A2 (ELF-1) has been described as the ligand for EphA4, ephrin-A3 (Ehk1-L) as the ligand for EphA5 and ephrin-B2 (Htk-L) as the ligand for EphB4 (Htk) (4–7).Function : Receptor for members of the ephrin-A family. Binds to EFNA3, EFNA4 and EFNA5.Subcellular Location : Isoform 1: Cell membrane; Single-pass type I membrane protein (Probable). Isoform 3: Cell membrane; Single-pass type I membrane protein (Probable). Isoform 2: Secreted (Probable).Tissue Specificity : Mainly expressed in testis.Similarity : Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.