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phospho-EGFR (Ser1142)磷酸化表皮生长因子受体抗体
点击次数：291发布时间：2012/12/5 15:59:39
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-5322R
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详细内容
货号：BY-5322R
英文名称：Anti-phospho-EGFR （Ser1142）
中文名称：磷酸化表皮生长因子受体抗体
其他名称：名EGFR; Avian erythroblastic leukemia viral （v erb b） oncogene homolog; Avian erythroblastic leukemia viral （verbb） oncogene homolog; Cell growth inhibiting protein 40; Cell proliferation inducing protein 61; EGF R; EGFR; Epidermal growth factor receptor （avian erythroblastic leukemia viral （v erb b） oncogene homolog）; Epidermal growth factor receptor （erythroblastic leukemia viral （v erb b） oncogene homolog avian）; Epidermal growth factor receptor; erbb 1; Erbb; Erbb1; HER1; mENA; Oncogene ERBB; PIG61; Receptor tyrosine protein kinase ErbB 1; Receptor tyrosine protein kinase ErbB1; Urogastrone; wa2; Wa5.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 170kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, rat, mo
产品介绍：Protein kinases are enzymes that transfer a phosphate group from a phosphate donor onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement ａnd cell movement, apoptosis, ａnd differentiation. The protein kinase family is one of the largest families of proteins in eukaryotes, classified in 8 major groups based on sequence comparison of their tyrosine （PTK） or serine/threonine （STK） kinase catalytic domains. Epidermal Growth factor receptor （EGFR） is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis ａnd is observed in tumors of the head ａnd neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach ａnd in squamous cell carcinoma.
