产品展示
ECE2内皮素转化酶2抗体
点击次数：263发布时间：2012/12/5 16:03:59
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-1753R
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详细内容
货号：BY-1753R
英文名称：Anti-ECE2
中文名称：内皮素转化酶2抗体
其他名称：名ECE2; MGC78487; ECE 2; Endothelin converting enzyme 2; Hypothetical protein MGC2408; KIAA0604; MGC17664.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 80-100kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, rat, mo
产品介绍：Endothelin-converting enzyme 2 （ECE2） converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, ａnd prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity. Expressed at high levels in central nervous system. Expressed in adrenal glands, ovary ａnd uterus, ａnd at low levels in heart.Subcellular Location : Golgi apparatus membrane; Single-pass type II membrane protein （By similarity）. Cytoplasmic granule membrane; Single-pass type II membrane protein （By similarity）.Tissue Specificity : Expressed in brain. Strongly down-regulated in inferior parietal lobe from Alzheimer disease patients （at protein level）.Similarity : In the N-terminal section; belongs to the methyltransferase superfamily. In the C-terminal section; belongs to the peptidase M13 family.
