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货号:BY-0983R
英文名称:Anti-EV71 polyprotein VP1
中文名称:肠道病毒71型抗体
其他名称:名EV71; Enterovirus 71.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 51kDa
纯化方法:affinity purified by Protein A
交叉反应:EV71
产品介绍:Enteroviruses, such as enterovirus 71, are classified to be in the picornavirus family, pico [small] + RNA [ribonucleic acid] + virus. Picornaviruses are among the smallest and simplest ribonucleic acid containing viruses known (1). The RNA for many enteroviruses have now been cloned and complete genomic sequences have been obtained. The RNA from all sequenced enteroviruses are similar in length, about 7400 nucleotides, and have identical organization (1). The human alimentary tract is the predominant site of enterovirus replication and these viruses were first isolated from enteric specimens. These viruses are the cause of paralytic poliomyelitis, aseptic meningitis-encephalitis, myocarditis, pleurodynia, hand-foot-and-mouth disease, conjunctivitis, and numerous other syndromes associated with extra-intestinal target organs. There are 67 numbered types of enteroviruses in the enterovirus family (1): three polioviruses, twenty-three coxsackieviruses A, six coxsackieviruses B, thirty-one echoviruses, and four other enteroviruses. 肠道病毒71型(Human enterovirus 71)简称EV71。肠病毒在病毒学上的分类是属于微小病毒科(picornaviridae)中的肠病毒群(enterovirus)。EV 71为目前肠病毒群中*新发现的病毒,其感染性强且致病率高,尤其是神经系统方面的并发症。EV71主要引起手足口病,还可引起无菌性脑膜炎、脑干脑炎和脊髓灰质炎样的麻痹等多种神经系统疾病。手足口病和中枢神经系统感染是EV71感染而引起的两大常见临床症状。 肠道病毒71型病毒从咽部或肠道侵入,在局部黏膜或淋巴组织中繁殖,并由局部排出,此时可引起局部症状。继而病毒又侵入局部淋巴结,并由此进入血液循环导致次病毒血症。病毒经血循环侵入网状内皮组织、深层淋巴结、肝、脾、骨髓等处大量繁殖并由此进入血液循环,引起第二次病毒血症。病毒可随血流进入全身各器官,如中枢神经系统、皮肤黏膜、心脏等处,进一步繁殖并引起病变。Mol wt: 7.6kDa、141KDa产品图片Antigen: bs-0983P, 0.2ug/100ul Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Goat-Anti- Rabbit IgG(bs-0295G-HRP) at 1: 5000; TMB(C-0024) staining; Read the data in MicroplateReader by 450nm.