产品展示
EFHC2EFHC2蛋白抗体
点击次数：272发布时间：2012/12/5 16:21:27
更新日期：2024/9/5 14:43:01
所 在 地：中国大陆
产品型号：BY-9014R
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详细内容
货号：BY-9014R
英文名称：Anti-EFHC2
中文名称：EFHC2蛋白抗体
其他名称：名EF hand domain （C terminal） containing 2;EF hand domain containing family member C2;EF-hand domain-containing family member C2;FLJ22601;FLJ22843;dJ1158H2.1;DKFZp686G08235.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 87kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：EFHC2 contains 3 DM10 domains, followed by 3 putative EF-hand motifs. There are two named isoforms produced by alternative splicing. EFHC2 can be used as a quantitative trait locus for fear recognition in Turner syndrome.EF-HC2 is a 749 amino acid protein containing three DM10 domains ａnd an EF-hand domain. EF-HC2 shares 41.6% homology with EF-HC1, ａnd is widely expressed in peripheral tissues ａnd central nervous system. The gene encoding EF-HC2 maps to human chromosome Xp11.3 ａnd is critical for recognition of facial fear ａnd harm avoidance. Turner syndrome, characterized by deficits in social cognition ａnd recognition of facial fear, has been linked to the EF-HC2 gene. Deletion of the EF-HC2 gene may be associated with Norrie disease, an X-linked disorder that primarily effects the eye, ａnd may also be linked to juvenile myoclonic epilepsy. EF-HC2 exists as two isoforms due to alternative splicing events.
