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EphA3/Eph receptor A3酪氨酸蛋白激酶受体A3抗体
点击次数：239发布时间：2012/12/5 16:24:01
更新日期：2024/9/5 14:43:14
所 在 地：中国大陆
产品型号：BY-7032R
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详细内容
货号：BY-7032R
英文名称：Anti-EphA3/Eph receptor A3
中文名称：酪氨酸蛋白激酶受体A3抗体
其他名称：名EK4;End3;Eph receptor A3;EPH-like kinase 4;EPH-like tyrosine kinase 1;EphA3;Ephrin receptor EphA3;Ephrin type-A receptor 3;ETK 1;ETK;ETK1;HEK 4;HEK;Hek4;Human embryo kinase;Mek4;MGC109882;Receptor tyrosine kinase HEK;Tyro 4;Tyro4;Tyrosine protein kinase receptor ETK 1;Tyrosine-protein kinase TYRO4;AW492086;Cek4;EC 2.7.10.1.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 110kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：EphA3 is a member of the Ephrin （Eph） family. The Ephrins ａnd Eph-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases ａnd have been implicated in mediating developmental events, especially in the nervous system ａnd in erythropoiesis. Based on their structures ａnd sequence relationships, ephrins are divided into the Ephrin A （EphA） class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, ａnd the Ephrin B （EphB） class, which are transmembrane proteins. Receptors in the EPH subfamily typically have a single kinase domain ａnd an extracellular region containing a Cys-rich domain ａnd 2 fibronectin type III repeats.Function : Receptor for members of the ephrin-A family. Binds to ephrin-A2, -A3, -A4 ａnd -A5. Could play a role in lymphoid function.Subunit : Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.Contains 2 fibronectin type-III domains.Contains 1 protein kinase domain.Contains 1 SAM （sterile alpha motif） domain.Subcellular Location : Secreted ａnd Cell membrane.Tissue Specificity : Widely expressed. Highest level in placenta.DISEASE : Defects in EPHA3 may be a cause of colorectal cancer （CRC）
