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Phospho-EEF2k (Ser366)磷酸化真核延伸因子激酶2抗体
点击次数：661发布时间：2012/12/5 16:29:16
更新日期：2024/9/5 14:43:14
所 在 地：中国大陆
产品型号：BY-3487R
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货号：BY-3487R
英文名称：Anti-Phospho-EEF2k （Ser366）
中文名称：磷酸化真核延伸因子激酶2抗体
其他名称：名Calcium/calmodulin dependent eukaryotic elongation factor 2; Calcium/calmodulin dependent eukaryotic elongation factor 2 kinase; Calmodulin dependent protein kinase III; cb365; eEF 2 kinase; eEF 2K; EEF2K protein; Elongation factor 2 kinase; Eukaryotic elongation factor 2 kinase; kinase eEF2K; SMEF2K.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 80kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, rat, Rb, pig, cow, dog
产品介绍：Eukaryotic elongation factor 2 kinase （EEF2k） previously known as Ca2+/calmodulin dependent protein kinase III, is an abundant cytoplasmic protein highly specific for elongation factor 2 （eEf2）. Phosphorylation of eEF2 by eEF2 kinase on specific threonine residues results in the inactivation of eEF-2 ａnd in termination of mRNA translation. The activity of eEF2 kinase is not only dependent upon Ca2+ ions, calmodulin （CaM） ａnd insulin, but is also regulated both negatively ａnd positively via phosphorylation by different protein kinases （AMPK, S6K1, p90 RSK）. There is also evidence that eEF-2 phosphorylation is involved in the regulation of cell cycle progression, cellular differentiation, oogensis ａnd malignant tumors.Subunit : Monomer or homodimer.Similarity : "Belongs to the protein kinase superfamily. Alpha-type protein kinase family. Contains 1 alpha-type protein kinase domain.
