产品展示
Anti-APLP2淀粉样蛋白β前体样蛋白2抗体
点击次数：260发布时间：2012/12/26 1:40:21
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-8462R
优质供应
详细内容
货号：BY-8462R
英文名称：Anti-APLP2
中文名称：淀粉样蛋白β前体样蛋白2抗体
其他名称：amyloid beta （A4） precursor like protein 2; Amyloid like protein 2; amyloid precursor protein homolog HSD2; Amyloid protein homolog; Amyloid-like protein 2; APLP-2; Aplp2; APLP2_HUMAN; APPH; APPL2; CDEBP; CDEI box binding protein; CDEI box-binding protein.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 80kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, chk, pig, hrs
产品介绍：APLP2 is a human sperm membrane protein which contains a segment with high homology to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer disease patients. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. The gene which encodes APLP2 maps to human chromosome 11q24.May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5＇-GTCACATG-3＇（CDEI box）. Inhibits trypsin, chymotrypsin, plasmin, factor XIA ａnd plasma ａnd glandular kallikrein.Function : May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5＇-GTCACATG-3＇（CDEI box）. Inhibits trypsin, chymotrypsin, plasmin, factor XIA ａnd plasma ａnd glandular kallikrein.Subunit : Interacts with CPEB1.Subcellular Location : Cell membrane. Nucleus.Tissue Specificity : Expressed in placenta, brain, heart, lung, liver, kidney ａnd endothelial tissues.Post-translational modifications : The BPTI/Kunitz inhibitor domain is O-glycosylated.Similarity : Belongs to the APP family.Contains 1 BPTI/Kunitz inhibitor domain.
