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Anti-APLP1淀粉样蛋白β前体样蛋白1抗体
点击次数：241发布时间：2012/12/26 1:40:48
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-8465R
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货号：BY-8465R
英文名称：Anti-APLP1
中文名称：淀粉样蛋白β前体样蛋白1抗体
其他名称：AMYLOID BETA A4 PRECURSOR-LIKE PROTEIN 1;AMYLOID PRECURSOR-LIKE PROTEIN;Amyloid-like protein 1 precursor;APLP 1;APLP;APLP-1;Aplp1;APLP1_HUMAN;C30.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 72kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 （Fe65） binding （By similarity）. Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin ａnd collagen I.The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis.Subcellular Location : Cell membrane ａnd Cytoplasm. C-terminally processed in the Golgi complex.Tissue Specificity : Expressed in the cerebral cortex where it is localized to the postsynaptic density （PSD）.
