产品展示
Anti-ACL6B/BAF53b肌动蛋白样蛋白6B抗体
点击次数：300发布时间：2012/12/26 1:44:19
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-11195R
优质供应
详细内容
货号：BY-11195R
英文名称：Anti-ACL6B/BAF53b
中文名称：肌动蛋白样蛋白6B抗体
其他名称：53 kDa BRG1 associated factor B;ACL 6B;ACL6B;Actin like 6;Actin like protein 6B;Actin like protein6B;Actin related protein;Actin related protein Baf53b;actin-like 6B;Actl 6;ACTL 6B;Actl6;ACTL6 B;ACTL6B;Arp Na;ArpN a;ArpN alpha;ArpNa;ArpNalpha;Baf 53b.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 47kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：BAF53b is a member of a family of actin-related proteins （ARPs）, which shares significant sequence identity with conventional actins. Both actins ａnd ARPs comprise an actin fold, which forms an ATP binding cleft. BAF53b is a component of the BAF （BRG/brm-associated factor） complex in mammals, which is functionally related to the SWI/SNF complex in S. cerevisiae ａnd Drosophila, ａnd is associated with chromatin remodelling to facilitate transcriptional activation. As neural progenitors exit the cell cycle, the highly homologous BAF53a subunit of the BAF complex is replaced by BAF53b. This subunit switch is essential for the transition from from neural stem cells / progenitors to postmitotic neurons. BAF53b also plays a role in dendritic outgrowth, during which it is required to recruit the BAF complex ａnd the dendritic regulator CREST to specific gene promoters. This function can not be performed by BAF53a. Subcellular Location : Nuclear
