产品展示
Anti-ARL8BADP核糖基化样因子8B抗体
点击次数：264发布时间：2012/12/26 1:48:06
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-9304R
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详细内容
货号：BY-9304R
英文名称：Anti-ARL8B
中文名称：ADP核糖基化样因子8B抗体
其他名称：ADP ribosylation factor like 10C;ADP-ribosylation factor-like protein 10C;ADP-ribosylation factor-like protein 8B;ARL10C;ARL8B;ARL8B_HUMAN;FLJ10702;Gie1;Novel small G protein indispensable for equal chromosome segregation 1.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 22kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：ADP-ribosylation factors （ARFs） are highly conserved guanine nucleotide binding proteins that enhance the ADP-ribosyltransferase activity of Cholera Toxin. ARF’s are important in eukaryotic vesicular trafficking pathways ａnd they play an essential role in the activation of phospholipase D （PC-PLD）. ARL8B （ADP-ribosylation factor-like protein 8B）, also known as ARL10C or GIE1, is a 186 amino acid protein that localizes to the late endosome membrane ａnd belongs to the ARL family of ARF-like GTPase proteins. Expressed ubiquitously, ARL8A interacts with Tubulin ａnd is thought to play a role in lysosome motility, as well as in chromosomal segregation. The gene encoding ARL8B maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor （CKR） gene cluster ａnd a variety of human cancer-related gene loci.Subcellular Location : Late endosome membrane. Lysosome membrane. Cytoplasm > cytoskeleton > spindle.Tissue Specificity : Ubiquitously expressed.
