本公司经销Adiponectin receptor 2，脂联素受体2抗体，克隆类型为polyclonal，宿主来源是Rabbit，Adiponectin receptor 2脂联素受体2抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-0611R
英文名称：Anti-Adiponectin receptor 2
中文名称：脂联素受体2抗体
其他名称：Adipo R2; Progestin ａnd adipoQ receptor family member II; Adipor2; PAQR2.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 42kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, rat, mo, dog
产品介绍：The adiponectin receptors, ADIPOR1 ａnd ADIPOR2 （MIM607946）, serve as receptors for globular ａnd full-length adiponectin （MIM 605441） ａnd mediate increased AMPK （see MIM602739） ａnd PPAR-alpha （PPARA; MIM 170998） ligand activities, as well as fatty acid oxidation ａnd glucose uptake by adiponectin.Function : Receptor for globular ａnd full-length adiponectin （APM1）, an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation ａnd glucose uptake by adiponectin. Has some intermediate-affinity receptor activity for both globular ａnd full-length adiponectin.Subunit : May form homo ａnd heteromultimers.Subcellular Location : Membrane; Multi-pass membrane protein. Note=Localized to the cell membrane ａnd intracellular organelles.Tissue Specificity : Highly expressed in skeletal muscle, liver ａnd placenta. Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes ａnd lung.Similarity : Belongs to the ADIPOR family.脂联素与受体结合后具有增强胰岛素敏感性，抗高血糖，抗动脉粥样硬化等生物学效应，任何增加或减少脂联素及其受体表达的方法都影响这些疾病的发生和发展。脂联素受体（AdipoR1和AdipoR2）同属于PAQR家族，具有七次跨膜蛋白的特有结构.产品图片Tissue/cell: rat pancreas tissue; 4% Paraformaldehyde-fixed ａnd paraffin-embedded; Antigen retrieval: citrate buffer （ 0.01M, pH 6.0 ）, Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer （normal goat serum,C-0005） at 37℃ for 20 min; Incubation: Anti-Adiponectin Receptor 1 Polyclonal Antibody, Unconjugated（bs-0610R） 1:200, overnight at 4°C, followed by conjugation to the secondary antibody（SP-0023） ａnd DAB（C-0010） stainingTissue/cell: human rectal tissue; 4% Paraformaldehyde-fixed ａnd paraffin-embedded; Antigen retrieval: citrate buffer （ 0.01M, pH 6.0 ）, Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer （normal goat serum,C-0005） at 37℃ for 20 min; Incubation: Anti-Adiponectin Receptor 1 Polyclonal Antibody, Unconjugated（bs-0610R） 1:300, overnight at 4°C, followed by conjugation to the secondary antibody（SP-0023） ａnd DAB（C-0010） staining