产品展示
Anti-ANKRD1/CARP心肌锚蛋白重复结构域1抗体
点击次数：218发布时间：2012/12/26 1:58:20
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-8074R
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货号：BY-8074R
英文名称：Anti-ANKRD1/CARP
中文名称：心肌锚蛋白重复结构域1抗体
其他名称：ALRP; ANKR1_HUMAN; ANKRD 1; ANKRD1; Ankyrin repeat domain 1 （cardiac muscle）; Ankyrin repeat domain containing protein 1; Ankyrin repeat domain-containing protein 1; C 193; C193; Cardiac ankyrin repeat protein; CARP; CVARP; Cytokine inducible nuclear protein; Cytokine-inducible gene C-193 protein; Cytokine-inducible nuclear protein; HA1A2; Liver ankyrin repeat domain 1; MCARP.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 36kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, pig, shp, cow, Rb
产品介绍：May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells.Function : May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells.Subunit : Interacts with YBX1 （By similarity）. Interacts with TTN/titin.Subcellular Location : Nucleus.Tissue Specificity : Mainly expressed in activated vascular endothelial cells. To a lower extent, also expressed in hepatoma cells.DISEASE : Defects in ANKRD1 may be a cause of total anomalous pulmonary venous return （TAPVR） . TAPVR is a rare congenital heart disease （CHD） in which the pulmonary veins fail to connect to the left atrium during cardiac development, draining instead into either the right atrium or one of its venous tributaries. This disease accounts for 1.5% of all CHDs ａnd has a prevalence of approximately 1 out of 15＇000 live births.Similarity : Contains 5 ANK repeats.
