产品展示
Anti-AGXT2L2AGXT2L2蛋白抗体
点击次数：203发布时间：2012/12/26 2:01:23
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-9095R
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详细内容
货号：BY-9095R
英文名称：Anti-AGXT2L2
中文名称：AGXT2L2蛋白抗体
其他名称：Alanine glyoxylate aminotransferase 2 like 2;MGC117348.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 50kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cow, dog
产品介绍：Members of the class-III pyridoxal-phosphate-dependent aminotransferase family, such as AGXT2, catalyze the conversion of glyoxylate to glycine using L-alanine as the amino donor. AGXT2 protects from asymmetric dimethylarginine （ADMA）-induced inhibition in nitric oxide （NO） production. Elevated blood concentrations of ADMA, a methyl derivate of the amino acid arginine ａnd an endogenous inhibitor of nitric oxide （NO） synthase, is produced by the physiological degradation of methylated proteins ａnd is found in association with diabetes, hypertension, congestive heart failure ａnd atherosclerosis. AGXT2L2 （alanine-glyoxylate aminotransferase 2-like 2） is a 450 amino acid pyridoxal phosphate that exists as a homotetramer. Belonging to the class-III pyridoxal-phosphate-dependent aminotransferase family, AGXT2L2 localizes to the mitochondria ａnd exists as three alternatively spliced isoforms. Encoded by a gene located on human chromosome 5q35.3, AGXT2L2 may have similar functions as AGXT2.Subcellular Location : Mitochondrial
