本公司经销APOB48R，载脂蛋白B受体抗体，克隆类型为polyclonal，宿主来源是Rabbit，APOB48R载脂蛋白B受体抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-6336R
英文名称：Anti-APOB48R
中文名称：载脂蛋白B受体抗体
其他名称：apo b-100; APOB; apoB-48R; apoB-100R; apoB100R; Apolipoprotein B-100 receptor; Apolipoprotein B100 receptor; Apolipoprotein B48 receptor.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 115kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, dog, Rb
产品介绍：APOB48R is a macrophage receptor that binds to the apolipoprotein B48 of dietary triglyceride （TG） rich lipoproteins. It may provide essential lipids, lipid soluble vitamins ａnd other nutrients to reticuloendothelial cells.Function : Macrophage receptor that binds to the apolipoprotein B48 （APOB） of dietary triglyceride （TG）-rich lipoproteins （TRL） or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein （HTG-VLDL）. Binds ａnd internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL ａnd remnant lipoprotein （RLP）. Mediates the rapid high-affinity uptake of chylomicrons （CM）, HTG-VLDL, ａnd trypsinized （tryp） VLDL devoid of APOE in vitro in macrophages.Subunit : Homodimer.Subcellular Location : Cell membrane; Peripheral membrane protein. Note=Binds monocyte-macrophage membrane. Thought to be anchored in the membrane through an interaction with an integral membrane protein.Tissue Specificity : Expressed in peripheral blood leukocytes > bone marrow = spleen > lymph node, ａnd only faintly visible in appendix ａnd thymus. Expressed in the brain, heart, kidney, liver, lung, pancreas, ａnd placenta. Expressed primarily by reticuloendothelial cells: monocytes, macrophages, ａnd endothelial cells. Expressed in atherosclerotic lesion foam cells.Post-translational modifications : There are 2 forms in macrophages, the membrane-binding proteins 200 kDa （MBP 200） ａnd 235 kDa （MBP 235）, that can be reduced into a single active ligand-binding species with intermediate mobility （MBP 200R）.