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Anti-ACE1/CD143血管紧张素转换酶ACE1抗体
点击次数:199发布时间:2012/12/26 2:10:04
更新日期:2024/9/5 14:43:27
所 在 地:其它
产品型号:BY-0439R
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货号:BY-0439R
英文名称:Anti-ACE1/CD143
中文名称:血管紧张素转换酶ACE1抗体
其他名称:Angiotensin Converting Enzyme 1; ACE; ACE-T; Angiotensin-converting enzyme isoform 1precursor; Dipeptidyl carboxy peptidase 1; Kininase II; ACE-1;testis-specific isoform precursor.ACE 1; ACE T; ACE1; Angiotensin converting enzyme somatic isoform; Angiotensin converting enzyme testis specific isoform; Angiotensin I converting enzyme; Angiotensin I converting enzyme 1; Angiotensin I converting enzyme peptidyl dipeptidase A 1; Carboxycathepsin; CD 143; CD143; CD143 antigen; DCP 1; DCP; DCP1; Dipeptidyl carboxypeptidase 1; MVCD3; Peptidase P; Peptidyl dipeptidase A; Testicular ECA.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 181kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, rat, mo, shp, dog, pig, cow
产品介绍:Angiotensin Converting enzyme is involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.合成与降解(Synthesis and Degradation)ACE的主要功能是转化血管紧张素Ⅰ为血管紧张素Ⅱ,后者有升高血压的作用。大多数结节病活动期ACE活性升高. 产品图片Tissue/cell: rat pancreas tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-ACE1 Polyclonal Antibody, Unconjugated(bs-0439R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining