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Anti-AcinusAcinus抗体
点击次数：273发布时间：2012/12/26 2:11:02
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-0120R
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详细内容
货号：BY-0120R
英文名称：Anti-Acinus
中文名称：Acinus抗体
其他名称：ACIN 1; ACIN1; ACINUS; CAN; Apoptotic chromatin condensation inducer 1; Apoptotic chromatin condensation inducer in the nucleus; DKFZp667N107; KIAA0670.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 67kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cow, hrs, dog
产品介绍：Chromatin condensation ａnd nuclear fragmentation （CCNF） are the hallmarks of apoptosis. CCNF is triggered by the activation of members of the caspase family, caspase activated DNase （CAD/DFF40）, ａnd several novel proteins including AIF ａnd CIDE. A new inducer of chromatin condensation was recently identified ａnd designated Acinus （for apoptotic chromatin condensation inducer in the nucleus）. Acinus is cleaved by Caspase 3 ａnd an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human ａnd mouse ａnd designated Acinus L （1341 amino acids）, Acinus S （583 amino acids） ａnd Acinus S＇ （614 amino acids）
