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Anti-ACTH (1-39)促肾上腺皮质激素(1-39)抗体
点击次数:213发布时间:2012/12/26 2:11:53
更新日期:2024/9/5 14:43:27
所 在 地:其它
产品型号:BY-0443R
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详细内容
货号:BY-0443R
英文名称:Anti-ACTH (1-39)
中文名称:促肾上腺皮质激素(1-39)抗体
其他名称:Adrenocorticotropic hormone; Adrenocorticotropin; Adrenocorticotropin Hormone; Alpha Melanocyte Stimulating Hormone; Beta Lipotropin; Beta Melanocyte Stimulating Hormone; CLIP; Corticotropin; Corticotropin Like Intermediary Peptide; Corticotropin lipotropin precursor; Lipotropin Beta; Lipotropin Gamma;LPH; Melanotropin Alpha; Met Enkephalin; MSH; NPP; POC; POMC; Pro opiomelanocortin; Proopiomelanocortin.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 4.3kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, rat, mo, cow, go
产品介绍:The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.促肾上腺皮质激素(Adrenorticotrophin hormons, ACTH)是垂体前叶细胞分泌的一种多肽激素,是肾上腺皮质活性的主要调节者。此抗体可与人的ACTH反应,与多种其它哺乳动物的ACTH有交叉反应,可用于垂体腺瘤的功能性分类,有助于区分原发性和转移型垂体肿瘤,嗜络细胞瘤等部分神经内分泌肿瘤也可出现阳性反应.产品图片Antigen: bs-0443P, 0.2ug/100ul Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Goat-Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000; TMB(C-0024) staining; Read the data in MicroplateReader by 450nm.