产品展示
Anti-ACTH (18-39)促肾上腺皮质激素ACTH(18-39)抗体
点击次数：194发布时间：2012/12/26 2:12:21
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-0442R
优质供应
详细内容
货号：BY-0442R
英文名称：Anti-ACTH （18-39）
中文名称：促肾上腺皮质激素ACTH（18-39）抗体
其他名称：Adrenocorticotropic hormone; Adrenocorticotropin; Adrenocorticotropin Hormone; Alpha Melanocyte Stimulating Hormone; Beta Lipotropin; Beta Melanocyte Stimulating Hormone; CLIP; Corticotropin; Corticotropin Like Intermediary Peptide; Corticotropin lipotropin precursor; Lipotropin Beta; Lipotropin Gamma; LPH; Melanotropin Alpha; Met Enkephalin; MSH; NPP; POC; POMC; Pro opiomelanocortin; Proopiomelanocortin
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 4.5kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, rat, mo
产品介绍：The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis ａnd the maintenance of normal adrenal weight, ａnd lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, ａnd epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain ａnd energy homeostasis, melanocyte stimulation, ａnd immune modulation. These include several distinct melanotropins, lipotropins, ａnd endorphins that are contained within the adrenocorticotrophin ａnd beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, ａnd red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.促肾上腺皮质激素（Adrenorticotrophin hormons, ACTH）是垂体前叶细胞分泌的一种多肽激素，是肾上腺皮质活性的主要调节者。此抗体可与人的ACTH反应,与多种其它哺乳动物的ACTH有交叉反应，可用于垂体腺瘤的功能性分类，有助于区分原发性和转移型垂体肿瘤，嗜络细胞瘤等部分神经内分泌肿瘤也可出现阳性反应.
