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货号:BY-0004R
英文名称:Anti-ACTH (7-23)
中文名称:促肾上腺皮质激素ACTH (7-23)抗体
其他名称:Adrenocorticotropic hormone; Adrenocorticotropin; Adrenocorticotropin Hormone; Alpha Melanocyte Stimulating Hormone; Beta Endorphin; Beta Lipotropin; Beta Melanocyte Stimulating Hormone; CLIP; Corticotropin; Corticotropin Like Intermediary Peptide; Corticotropin lipotropin precursor; Lipotropin Beta; Lipotropin Gamma; LPH; Melanotropin Alpha; Met Enkephalin; MSH; NPP; POC; POMC; Pro opiomelanocortin; Proopiomelanocortin.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 4.3kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, Gpig, cow, pig, dog, Rb
产品介绍:ACTH occurs in cells of the anterior pituitary and in neurons in brain. It regulates the corticosteroid production in the adrenal cortex. Beta endorphin and Met enkephalin are endogenous opiates. MSH (melanocyte stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes. Function : ACTH stimulates the adrenal glands to release cortisol.MSH (melanocyte-stimulating hormone) increases thepigmentation of skin by increasing melanin production in melanocytes.Beta-endorphin and Met-enkephalin are endogenous opiates.Subunit : Belongs to the POMC family.Subcellular Location : Secreted.Tissue Specificity : ACTH and MSH are produced by the pituitary gland.DISEASE : Defects in POMC may be associated with susceptibility to obesity (OBESITY) [MIM:601665]. It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.Defects in POMC are the cause of pro-opiomelanocortinin deficiency (POMCD) [MIM:609734]. Affected individuals present early-onset obesity, adrenal insufficiency and red hair.Similarity : Belongs to the POMC family.促肾上腺皮质激素(Adrenorticotrophin hormons, ACTH)是垂体前叶细胞分泌的一种多肽激素,是肾上腺皮质活性的主要调节者。此抗体可与人的ACTH反应,与多种其它哺乳动物的ACTH有交叉反应,可用于垂体腺瘤的功能性分类,有助于区分原发性和转移型垂体肿瘤,嗜络细胞瘤等部分神经内分泌肿瘤也可出现阳性反应。