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Anti-AP2 alpha转录激活蛋白2α抗体
点击次数：222发布时间：2012/12/26 2:16:57
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-3569R
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货号：BY-3569R
英文名称：Anti-AP2 alpha
中文名称：转录激活蛋白2α抗体
其他名称：TFAP2α; Activating enhancer binding protein 2 alpha; AP-2α; activating protein 2α; Activator protein 2; AP 2; AP 2 transcription factor; AP 2alpha; AP2; AP2 Transcription Factor; AP2TF; Clathrin Adaptor Protein Complex; TFAP 2; TFAP 2A; TFAP2; TFAP2A; Transcription factor AP 2 alpha （activating enhancer binding protein 2 alpha）;AP-2a;AP 2a; AP2a; Transcription factor AP 2 alpha; Transcription factor AP2 alpha.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 48kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, pig, hrs, Rb, cow, chk, shp, dog
产品介绍：Activation Protein transcription factor 2 （AP2） is a developmentally regulated transcription factor that recognizes a specific sequence CCCCAGGC or related sequences present in several promoter ａnd enhancer gene regions including the promoters of the AP2 genes themselves. There are three different but highly homologous AP2 isoforms: alpha, beta, ａnd gamma （ERF-1）, encoded by three different retinoic acid-responsive genes. Each form of AP2 possesses the DNA binding domain （basic helix-span-helix motif） characteristic of this family of transcription factors. The AP2 proteins are normally expressed in ectodermally derived vertebrate tissues where they are necessary for normal growth ａnd development. The factors have also been implicated in the control of cell proliferation, viral transformation, ａnd oncogenesis. AP2 seems to play in important role in human breast cancer.转录因子AP-2α在哺乳动物发育、分化以及肿瘤的发生等生命现象中起重要作用.
