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Anti-ADCK2ADCK2蛋白抗体
点击次数:220发布时间:2012/12/26 2:36:26
更新日期:2024/9/5 14:43:27
所 在 地:其它
产品型号:BY-7952R
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货号:BY-7952R
英文名称:Anti-ADCK2
中文名称:ADCK2蛋白抗体
其他名称:AARF; aarF domain containing kinase 2; ADCK2; ADCK2_HUMAN; MGC20727; Uncharacterized aarF domain-containing protein kinase 2.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 69kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, cow, hrs, chk, Rb
产品介绍:ADCK2 (aarF domain containing kinase 2), also known as AARF, is a 626 amino acid single-pass membrane protein belonging to the protein kinase superfamily and the ADCK protein kinase family. The ADCK family consists of five paralogs in human (ADCK1-5). Encoded by a gene that maps to human chromosome 7q34, ADCK2 contains one protein kinase domain. ADCK2 participates in ATP and nucleotide binding, transferase functions and protein serine/threonine kinase activities. Expression of ADCK2 inversely correlates with cellular viability, suggesting elevated expression of ADCK2 may be essential for tumour survival. ADCK2 is necessary for cell proliferation of glioblastoma multiforme (GBM), a fatal primary brain tumor containing countless genetic and epigenetic alterations.Function : The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr).Subcellular Location : Membrane; Single-pass membrane protein (Potential).Similarity : Belongs to the protein kinase superfamily. ADCK protein kinase family.Contains 1 protein kinase domain.