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Anti-AMIGO3粘附分子IgG样结构域蛋白3抗体
点击次数：255发布时间：2012/12/26 2:37:28
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-7959R
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货号：BY-7959R
英文名称：Anti-AMIGO3
中文名称：粘附分子IgG样结构域蛋白3抗体
其他名称：Adhesion molecule with Ig like domain 3; ALI3; Alivin 3; AMIGO 3; Amphoterin induced gene ａnd ORF 3; Amphoterin induced protein 3 precursor.AMGO3_HUMAN
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 52kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, pig, Rb
产品介绍：The amphoterin-induced gene ａnd ORF （AMIGO） family of proteins consists of AMIGO1, AMIGO2 ａnd AMIGO3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain, ａnd a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues ａnd participate in their formation. The AMIGO proteins can form complexes with each other, but can also bind itself. AMIGO1, also designated Alivin-2, promotes growth ａnd fasciculation of neurites ａnd plays a role in myelination ａnd fasciculation of developing neural axons. In cerebellar neurons, AMIGO2 （Alivin-1） is crucial for depolarization-dependent survival. Similar to AMIGO1 ａnd AMIGO2, AMIGO3 （Alivin-3） plays a role in homophilic and/or heterophilic cell-cell interaction ａnd signal transduction.Function : AMIGO3 may mediate heterophilic cell-cell interaction ａnd may also contribute to signal transduction through its intracellular domain.Subunit : Binds AMIGO1 or AMIGO2 （By similarity）.Subcellular Location : Membrane; Single-pass type I membrane proteinSimilarity : Belongs to the immunoglobulin superfamily. AMIGO family.Contains 1 Ig-like C2-type （immunoglobulin-like） domain.Contains 6 LRR （leucine-rich） repeats.Contains 1 LRRCT domain.Contains 1 LRRNT domain.
