本公司经销Angiotensin II，血管紧张素Ⅱ抗体，克隆类型为polyclonal，宿主来源是Rabbit，Angiotensin II血管紧张素Ⅱ抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-0587R
英文名称：Anti-Angiotensin II
中文名称：血管紧张素Ⅱ抗体
其他名称：Alpha 1 antiproteinase, antitrypsin; Ang II; ANG III; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensinogen; Angiotensinogen （serpin peptidase inhibitor, clade A member 8）; ANHU; Pre angiotensinogen; Serine （or cysteine） proteinase inhibitor; Serpin A8; SERPINA8; AT-2; AT-II.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 53kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, hrs, shp
产品介绍：AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver ａnd is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme （ACE） to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure ａnd in the pathogenesis of essential hypertension ａnd preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, ａnd can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, ａnd inflammatory bowel disease.血管紧张素II是调节血压、血容量的重要因子，也是一种可能的神经介质。Ang II 控制血压和体液平衡，但现在进一步认识到Ang II还与炎性改变有关.产品图片Antigen: bs-0587P, 0.2ug/100ul Primary: Antiserum of Rabbit-Anti-Angiotensin II （bs-0587R） at the dilution of 500, 1000, 2000, 4000, 8000, 16000, 32000; Secondary: HRP conjugated Goat-Anti-Rabbit IgG（bse-0295G） at 1: 5000; TMB（C-0024） staining; Read the data in MicroplateReader by 450nm. Tissue/cell: rat pancreas tissue; 4% Paraformaldehyde-fixed ａnd paraffin-embedded; Antigen retrieval: citrate buffer （ 0.01M, pH 6.0 ）, Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer （normal goat serum,C-0005） at 37℃ for 20 min; Incubation: Anti-Angiotensin II Polyclonal Antibody, Unconjugated（bs-0587R） 1:200, overnight at 4°C, followed by conjugation to the secondary antibody（SP-0023） ａnd DAB（C-0010） staining