本公司经销α-Adaptin，衔接蛋白α抗体，克隆类型为polyclonal，宿主来源是Rabbit，α-Adaptin衔接蛋白α抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-1228R
英文名称：Anti-α-Adaptin
中文名称：衔接蛋白α抗体
其他名称：alpha Adaptin; Adaptin-α; 100 kDa coated vesicle protein A; 100 kDa coated vesicle protein C; adaptin alpha A; Adaptin alpha B; Adaptor protein complex AP 2 alpha 1 subunit; Adaptor protein complex AP 2 alpha 2 subunit; Adaptor related protein complex 2 alpha 1 subunit; Adaptor related protein complex 2 alpha 2 subunit; ADTAA; ADTAB; Alpha adaptin A; Alpha adaptin C; AP 2 complex subunit alpha 1; AP 2 complex subunit alpha 2; AP2 alpha; AP2A1; AP2A2; CLAPA1; CLAPA2; Clathrin assembly protein complex 2 alpha A large chain; Clathrin assembly protein complex 2 alpha C large chain; Clathrin associated/assembly/adaptor protein large alpha 1; Clathrin associated/assembly/adaptor protein large alpha 2; HIP9; Huntingtin interacting protein HYPJ; Huntingtin interacting protein J; HYPJ; KIAA0899; Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit; Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 100-103kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cow, hrs, Rb
产品介绍：Clathrin-mediated endocytosis is the pathway by which many receptors for nutrients ａnd hormones are internalized to be recycled or down-regulated. During formation of clathrin coated membranes, clathrin co-assembles with heterotetrameric molecules known as assembly polypeptides （APs） or adaptors which form a layer of protein coat between the clathrin lattice ａnd the membrane. There are two characterized adaptors AP1 ａnd AP2. AP1 is associated with clathrin coated vesicles at the trans-Golgi network ａnd AP2 is associated with the endocytic clathrin coated vesicles at the plasma membrane ａnd has been shown to specifically interact with Shc ａnd EGF receptor. AP2 is composed of four subunits, two separate 100 kDa gene products with similar domain structures （alpha ａnd beta adaptin） ａnd a 50 ａnd 17 kDa subunit. There are two alpha-adaptin genes, alpha A ａnd alpha C which have a tissue specific pattern of expression. adaptin α参与披网格蛋白小泡组装的一种蛋白质, 在披网格蛋白小泡组装中与受体的细胞质结构域相互作用, 起衔接作用.