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货号：BY-0167R
英文名称：Anti-APOE/Apo E2
中文名称：载脂蛋白E抗体
其他名称：Apolipoprotein E precursor; AD2; Alzheimer disease 2; Apo E; ApoE; APOEA; ApolipoproteinE; Apoprotein; MGC1571; Apo E2; ApoE2; APOE 2; Apolipoprotein E; Apolipoprotein E2; LDLCQ5; LPG.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 30kDa
纯化方法：affinity purified by Protein A
交叉反应：mo, rat
产品介绍：Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells ａnd peripheral cells ａnd is essential for the normal catabolism of triglyceride-rich lipoprotein constituents.ApoE exists in three major isoforms; E2, E3, ａnd E4, which differ from one another by a single amino-acid substitution. Compared with E3 ａnd E4, E2 exhibits the lowest receptor binding affinity. Defects in ApoE are a cause of hyperlipoproteinemia type III due to increased plasma cholesterol ａnd triglycerides levels which are the consequence of impaired clearance of chylomicron ａnd VLDL remnants. ApoE 是在肝脏中合成的极低密度脂蛋白的组分，也是在细胞间转运胆固醇的高密度脂蛋白的一种亚类.
