本公司经销Aurora A/B/C，有丝分裂激酶A/B/C抗体，克隆类型为polyclonal，宿主来源是Rabbit，Aurora A/B/C有丝分裂激酶A/B/C抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-2751R
英文名称：Anti-Aurora A/B/C
中文名称：有丝分裂激酶A/B/C抗体
其他名称：AIK; ARK1; AURA; AURKA; Aurora 2; Aurora A; Aurora Family Kinase 1; aurora kinase A; Aurora Related Kinase 1; Aurora/IPL1 Like Kinase; Aurora/IPL1 Related Kinase 1; AURORA2; AYK1; BRAK; Breast Tumor Amplified Kinase; BTAK; hARK1; IAK; IPL1 Aurora Related Kinase 1; IPL1 Related Kinase; MGC34538.AIK2; AIM1; ARK2; AurB; AURKB; Aurora 1; Aurora ａnd Ipl1 like midbody associated protein 1; Aurora kinase B; Aurora related kinase 2; Aurora-B; Aurora/IPL1 related kinase 2; IPL1; Serine/theronine kinase 12; Serine/threonine protein kinase 12; STK1; STK12; STK5; AURKC; AIE2; AIK3; AurC; AURKC; Aurora C; Aurora/Ipl1 related kinase 3; IPL-1; Aurora/Ipl1/Eg2 protein 2; EC 2.7.11.1; Serine threonine protein kinase 13; STK13.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 36-39kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cow, Rb, hrs, pig
产品介绍：Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development ａnd progression ａnd is overexpressed in many human cancers including breast, ovarian ａnd colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Aurora B is a mitotic protein kinase that phosphorylates histone H3 （probably on Serine 10）, behaves as a chromosomal passenger protein, ａnd may regulate several stages of mitosis such as centrosome separation, chromosome segregation ａnd cytokinesis. It localizes to the inner centromere region from prophase to anaphase. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement ａnd segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 ａnd HeLa cells. Aurora-C expression is maximum at M phase.