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Anti-Phospho-Ack1(Tyr284)磷酸化Ack1抗体
点击次数:280发布时间:2012/12/26 3:24:41
更新日期:2024/9/5 14:43:27
所 在 地:其它
产品型号:BY-3045R
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货号:BY-3045R
英文名称:Anti-Phospho-Ack1(Tyr284)
中文名称:磷酸化Ack1抗体
其他名称:Acetate kinase 1; Acetokinase 1; Activated CDC42 kinase 1; Activated Cdc42 associated kinase 1; Activated p21cdc42Hs kinase; Tyrosine kinase non receptor 2; Tyrosine kinase non-receptor protein 2; non-receptor protein tyrosine kinase ACK; ACK; TNK 2; Tnk2; ACK1; FLJ44758; FLJ45547; p21cdc42Hs.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 114kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, pig, cow, dog
产品介绍:This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq.]Ack 1分子是一组促进酪氨酸激酶生长的家族成员,该蛋白与肿瘤分裂、生长、转移起到很重要的作用,可加速恶性肿瘤的浸润。