本公司经销AKR1B10，醛糖还原酶相关蛋白质抗体，克隆类型为polyclonal，宿主来源是Rabbit，AKR1B10醛糖还原酶相关蛋白质抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-6274R
英文名称：Anti-AKR1B10
中文名称：醛糖还原酶相关蛋白质抗体
其他名称：Aldose reductase like; Aldose reductase related protein; ARL 1; hARP; SI reductase; Small intestine reductase; AK1BA_HUMAN; AKR1B10; AKR1B11; AKR1B12; Aldo keto reductase family 1 member B10; aldo keto reductase family 1 member B11; Aldo-keto reductase family 1 member B10; aldose reductase like 1; aldose reductase like peptide; Aldose reductase-like; Aldose reductase-related protein; ALDRLn; ARL-1; ARL1; ARP; hARP; HIS; HSI; SI reductase; Small intestine reductase.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 35kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, Rb
产品介绍：AKR1B10 is also known as aldose reductase-like-1 （ARL-1）, small intestine reductase （SI reductase） or aldose reductase-related protein （ARP or hARP）. AKR1B10 is found in many tissues but is predominantly expressed in small intestine, colon ａnd adrenal gland. AKR1B10 is an efficient reductase for aliphatic ａnd aromatic aldehydes. It plays a role in steroid metabolism as well as detoxification of aldehydes in digested food, ａnd may be involved in the retinal-retinoic acid signaling pathway. AKR1B10 is prominently overexpressed in non-small cell lung carcinoma ａnd adenocarcinoma. Cigarette smoking is an independent variable responsible for this overexpression. AKR1B10 may play a role regulating cell proliferation ａnd cellular response to carbonyl stress.Function : Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic ａnd aromatic aldehydes, ａnd is less active on hexoses （in vitro）. May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.Subcellular Location : Lysosome. Secreted. Note=Secreted through a lysosome-mediated non-classical pathway.Tissue Specificity : Found in many tissues. Highly expressed in small intestine, colon ａnd adrenal gland.Similarity : Belongs to the aldo/keto reductase family.