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Anti-Azurocidin/Cationic antimicrobial protein 37肝素结合蛋白/阳离子抗菌蛋白37/天青杀素抗体
点击次数:265发布时间:2012/12/26 3:38:52
更新日期:2024/9/5 14:43:27
所 在 地:其它
产品型号:BY-7564R
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货号:BY-7564R
英文名称:Anti-Azurocidin/Cationic antimicrobial protein 37
中文名称:肝素结合蛋白/阳离子抗菌蛋白37/天青杀素抗体
其他名称:Azu 1; Azu1; Azurocidin; CAP37; CAP7_HUMAN; cationic antimicrobial protein 37; Cationic antimicrobial protein CAP37; HBP; Heparin binding protein; Heparin-binding protein; HUMAZUR.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 24kDa
纯化方法:affinity purified by Protein A
交叉反应:hu
产品介绍:This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. It may play a role in mediating recruitment of monocytes in the second wave of inflammation. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.Function : This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. It may play a role in mediating recruitment of monocytes in the second wave of inflammation. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. Acting alone, it does not have antimicrobial activity against the Gram-negative bacteria A.actinomycetemcomitans ATCC 29532, A.actinomycetemcomitans NCTC 9709, A.actinomycetemcomitans FDC-Y4, H.aphrophilus ATCC 13252, E.corrodens ATCC 23834, C.sputigena ATCC 33123, Capnocytophaga sp ATCC 33124, Capnocytophaga sp ATCC 27872 or E.coli ML-35. Has antibacterial activity against C.sputigena ATCC 33123 when acting synergistically with either elastase or cathepsin G.Subunit : Monomer.Subcellular Location : Belongs to the peptidase S1 family. Elastase subfamily.Contains 1 peptidase S1 domain.Similarity : Cytoplasmic granule. Note=Cytoplasmic granules of neutrophils.Belongs to the peptidase S1 family. Elastase subfamily.Contains 1 peptidase S1 domain.