本公司经销α-Synuclein，核突触蛋白抗体，克隆类型为polyclonal，宿主来源是Mouse，α-Synuclein核突触蛋白抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-0012M
英文名称：Anti-α-Synuclein
中文名称：核突触蛋白抗体
其他名称：Alpha synuclein; α Synuclein; Synuclein α; Alpha-synuclein, isoform NACP140; alphaSYN; MGC105443; MGC110988; MGC127560; MGC64356; NACP; Non A beta component of AD amyloid; Non A4 component of amyloid precursor; Non-A-beta component of alzheimers disease amyloid , precursor of; PARK 1; PARK 4; PARK1; PARK4; Parkinson disease familial 1; PD 1; PD1; SNCA; Snca synuclein, alpha （non A4 component of amyloid precursor）; Synuclein alpha; Synuclein, alpha （non A4 component of amyloid precursor）.
抗体来源：Mouse
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 15kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cow, hrs, shp, Gpig, dog
产品介绍：The synucleins, including alpha-synuclein （also designated NACP for nonamyloid component precursor）,beta-synuclein （also designated PNP 14 for phospho-neuroprotein 14）and gamma-synuclein （also designated persyn or BCSG1 for breast cancer-specific gene 1）are presynaptic protein abundant in neurons. alpha-synuclein, a component of Alzheimer’s disease amyloid plaques, is localized to neuronal cell bodies ａnd synapses. Coordinate expression of alpha-synucleinand beta-synuclein may be important during hematopoetic cell differentiation. In patients with Parkinson’s disease, a mutant form of alpha-synuclein has been found ａnd gamma-synuclein is associated with axonal pathology. Function : Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals.Subunit : Soluble monomer which can form filamentous aggregates. Interacts with UCHL1 （By similarity）. Interacts with phospholipase D ａnd histones.Subcellular Location : Cytoplasm. Membrane. Nucleus. Cell junction, synapse. Note=Membrane-bound in dopaminergic neurons.Tissue Specificity : Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals.Similarity : Belongs to the synuclein family.Synuclein 包括α-Synuclein，β-Synuclein 和γ-Synuclein 是神经细胞中富含的前突触蛋白。α-Synuclein，Alzheimer’（AD）病淀粉样蛋白沉积的成份，集中分布在神经细胞的包体和突触。在帕金森病人中发现有α-Synuclein的变异型，而γ-Synuclein与轴突病理学有关。此抗体将为Lewy小体痴呆症、Parkinson症、AD和其它一些神经性疾病提供有用的病理诊断。