产品展示
Anti-ADRB1肾上腺素能受体β1抗体
点击次数：228发布时间：2012/12/26 3:50:57
更新日期：2024/9/5 14:43:27
所 在 地：其它
产品型号：BY-0498R
优质供应
详细内容
货号：BY-0498R
英文名称：Anti-ADRB1
中文名称：肾上腺素能受体β1抗体
其他名称：beta 1 Adrenergic Receptor;ADRB1R;Adrenergic beta 1 receptor;B1AR;Beta 1 adrenoceptor;Beta 1 adrenoreceptor;Beta-1 adrenergic receptor;Beta-1 adrenoceptor;Beta-1 adrenoreceptor;BETA1AR;RHR.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 51-55kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, rat, mo, pig, dog
产品介绍：Beta-adrenergic receptors （Beta-1 adrenoreceptor） mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine ａnd norepinephrine with approximately equal affinity. Subcellular location cell membrane; Multi-pass membrane protein. Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase. Belongs to the G-protein coupled receptor 1 family.Subunit : Interacts with GOPC, MAGI3 ａnd DLG4.Subcellular Location : Cell membrane; Multi-pass membrane protein. Note=Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression.Similarity : Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB1 sub-subfamily.β1肾上腺素能受体（Beta-adrenergic Receptor-1 ）在接受交感神经节后纤维支配的各种器官中存在着与肾上腺素、去甲肾上腺素起反应的受体，称为肾上腺素能受体。其化学性质尚不清楚。用对药物反应的方法，肾上腺素能受体可分为α及β两个类型。肾上腺素对α、β及D型受体均起作用，而去甲肾上腺素主要对α型起作用。 β1AR所引起的反应为支气管扩张、血管扩张等，肾上腺素受体可被β13，4－dichloroisoproterenol（D－CI）等阻断药物所抑制。
